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TCR-like CARs and TCR-CARs targeting neoepitopes: an emerging potential

Neoepitopes or neoantigens are a spectrum of unique mutations presented in a particular patient’s tumor. Neoepitope-based adoptive therapies have the potential of tumor eradication without undue damaging effect on normal tissues. In this context, methods based on the T cell receptor (TCR) engineerin...

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Bibliografiska uppgifter
I publikationen:Cancer Gene Ther
Huvudupphovsmän: Poorebrahim, Mansour, Mohammadkhani, Niloufar, Mahmoudi, Reza, Gholizadeh, Monireh, Fakhr, Elham, Cid-Arregui, Angel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group US 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203496/
https://ncbi.nlm.nih.gov/pubmed/33654227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41417-021-00307-7
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