Active Tumoral/Tumor Environmental Dual-Targeting by Non-Covalently Arming with Trispecific Antibodies or Dual-Bispecific Antibodies on Docetaxel-Loaded mPEGylated Nanocarriers to Enhance Chemotherapeutic Efficacy and Minimize Systemic Toxicity

PURPOSE: This study was aimed at developing the trispecific antibodies (anti-EGFR/anti-FAP/anti-mPEG, TsAb) or dual bispecific antibodies (anti-EGFR/anti-mPEG and anti-FAP/anti-mPEG) docetaxel (DTX)-loaded mPEGylated lecithin-stabilized micelles (mPEG-lsbPMs) for improving the targeting efficiency a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Nanomedicine
Egile Nagusiak: Cheng, Wei-Jie, Lin, Shyr-Yi, Chen, Michael, Chen, Ling-Chun, Ho, Hsiu-O, Chuang, Kuo-Hsiang, Sheu, Ming-Thau
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove 2021
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203191/
https://ncbi.nlm.nih.gov/pubmed/34140769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S301237
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak