Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy

Progressive tumor growth is associated with deficits in the immunity generated against tumor antigens. Vaccines targeting tumor neoepitopes have the potential to address qualitative defects; however, additional mechanisms of immune failure may underlie tumor progression. In such cases, patients woul...

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Udgivet i:Cancer Immunol Res
Main Authors: Lee, Karin L., Benz, Stephen C., Hicks, Kristin C., Nguyen, Andrew, Gameiro, Sofia R., Palena, Claudia, Sanborn, John Z., Su, Zhen, Ordentlich, Peter, Rohlin, Lars, Lee, John H., Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Niazi, Kayvan, Schlom, Jeffrey, Hamilton, Duane H.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202970/
https://ncbi.nlm.nih.gov/pubmed/31292145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0620
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