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Acetyl oxygen benzoate engeletin ester promotes KLF4 degradation leading to the attenuation of pulmonary fibrosis via inhibiting TGFβ1–smad/p38MAPK–lnc865/lnc556–miR-29b-2-5p–STAT3 signal pathway

Pulmonary fibrosis is a common pulmonary interstitial disease of pathogenesis without effective drugs for treatment. Therefore, discovering new and effective drugs is urgently needed. In the present study, we prepared a novel compound named acetyl oxygen benzoate engeletin ester (AOBEE), investigate...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Aging (Albany NY)
Main Authors: Shen, Ke, Li, Ruiqiong, Zhang, Xiaoli, Qu, Guiwu, Li, Rongrong, Wang, Youlei, Liu, Bo, Lv, Changjun, Li, Minge, Song, Xiaodong
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202900/
https://ncbi.nlm.nih.gov/pubmed/33929970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202975
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