Engeletin ameliorates pulmonary fibrosis through endoplasmic reticulum stress depending on lnc949-mediated TGF-β1-Smad2/3 and JNK signalling pathways

CONTEXT: Pulmonary fibrosis (PF) is a highly heterogeneous and lethal pathological process having no effective drug. Engeletin exerts multiple biological activities including anti-inflammatory and lung repair. Whether engeletin has therapeutic effects on PF remains unclear. OBJECTIVE: Examining effe...

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Detalhes bibliográficos
Publicado no:Pharm Biol
Main Authors: Zhang, Jinjin, Chen, Xiaoqing, Chen, Hongbin, Li, Rongrong, Xu, Pan, Lv, Changjun, Liu, Bo, Song, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671710/
https://ncbi.nlm.nih.gov/pubmed/33181025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2020.1834590
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