Cdkn1a transcript variant 2 is a marker of aging and cellular senescence

Cellular senescence is a cell fate response characterized by a permanent cell cycle arrest driven primarily the by cell cycle inhibitor and tumor suppressor proteins p16(Ink4a) and p21(Cip1/Waf1). In mice, the p21(Cip1/Waf1) encoding locus, Cdkn1a, is known to generate two transcripts that produce i...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging (Albany NY)
Egile Nagusiak: López-Domínguez, José Alberto, Rodríguez-López, Sandra, Ahumada-Castro, Ulises, Desprez, Pierre-Yves, Konovalenko, Maria, Laberge, Remi-Martin, Cárdenas, César, Villalba, José Manuel, Campisi, Judith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals 2021
Gaiak:
Priority Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202863/
https://ncbi.nlm.nih.gov/pubmed/34035185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203110
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