Mesenchymal Stromal Cells From Emphysematous Donors and Their Extracellular Vesicles Are Unable to Reverse Cardiorespiratory Dysfunction in Experimental Severe Emphysema

Although bone marrow-derived mesenchymal stromal cells (BM-MSCs) from patients with chronic obstructive pulmonary disease (COPD) appear to be phenotypically and functionally similar to BM-MSCs from healthy sources in vitro, the impact of COPD on MSC metabolism and mitochondrial function has not been...

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Gepubliceerd in:Front Cell Dev Biol
Hoofdauteurs: Antunes, Mariana A., Braga, Cassia L., Oliveira, Tainá B., Kitoko, Jamil Z., Castro, Ligia L., Xisto, Debora G., Coelho, Mariana S., Rocha, Nazareth, Silva-Aguiar, Rodrigo P., Caruso-Neves, Celso, Martins, Eduarda G., Carvalho, Clara Fernandes, Galina, Antônio, Weiss, Daniel J., Lapa e Silva, José R., Lopes-Pacheco, Miquéias, Cruz, Fernanda F., Rocco, Patricia R. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Cell and Developmental Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202416/
https://ncbi.nlm.nih.gov/pubmed/34136481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.661385
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