Impact of one versus two doses of mesenchymal stromal cells on lung and cardiovascular repair in experimental emphysema

BACKGROUND: A single administration of mesenchymal stromal cells (MSCs) has been shown to reduce lung inflammation in experimental elastase-induced emphysema; however, effects were limited in terms of lung-tissue repair and cardiac function improvement. We hypothesized that two doses of MSCs could i...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Poggio, Hananda A., Antunes, Mariana A., Rocha, Nazareth N., Kitoko, Jamil Z., Morales, Marcelo M., Olsen, Priscilla C., Lopes-Pacheco, Miquéias, Cruz, Fernanda F., Rocco, Patricia R. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225700/
https://ncbi.nlm.nih.gov/pubmed/30409216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1043-6
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