Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions

The actin-related protein (ARP) 2/3 complex, essential for organizing and nucleating branched actin filaments, is required for several cellular immune processes, including cell migration and granule exocytosis. Recently, genetic defects in ARPC1B, a subunit of this complex, were reported. Mutations...

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Udgivet i:Front Immunol
Main Authors: Kempers, Lanette, Sprenkeler, Evelien G. G., van Steen, Abraham C. I., van Buul, Jaap D., Kuijpers, Taco W.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202084/
https://ncbi.nlm.nih.gov/pubmed/34135903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.678030
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