The Rhox gene cluster suppresses germline LINE1 transposition

Transposable elements (TEs) are mobile sequences that engender widespread mutations and thus are a major hazard that must be silenced. The most abundant active class of TEs in mammalian genomes is long interspersed element class 1 (LINE1). Here, we report that LINE1 transposition is suppressed in th...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Tan, Kun, Kim, Matthew E., Song, Hye-Won, Skarbrevik, David, Babajanian, Eric, Bedrosian, Tracy A., Gage, Fred H., Wilkinson, Miles F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2021
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201764/
https://ncbi.nlm.nih.gov/pubmed/34083437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024785118
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