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Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I
The natural product cepafungin I was recently reported to be one of the most potent covalent inhibitors of the 20S proteasome core particle through a series of in vitro activity assays. Here, we report a short chemoenzymatic total synthesis of cepafungin I featuring the use of a regioselective enzym...
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| Published in: | Cell Chem Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8201661/ https://ncbi.nlm.nih.gov/pubmed/32763140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.07.012 |
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