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Total Synthesis and Target Identification of the Curcusone Diterpenes

The curcusone natural products are complex diterpenes featuring a characteristic [6-7-5] tricyclic carbon skeleton similar to the daphnane and tigliane diterpenes. Among them, curcusones A-D demonstrated potent anticancer activity against a broad spectrum of human cancer cell lines. Prior to this st...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Cui, Chengsen, Dwyer, Brendan G., Liu, Chang, Abegg, Daniel, Cai, Zhong-Jian, Hoch, Dominic, Yin, Xianglin, Qiu, Nan, Liu, Jie-Qing, Adibekian, Alexander, Dai, Mingji
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281983/
https://ncbi.nlm.nih.gov/pubmed/33705657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c00557
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