Homocysteine-induced neural tube defects in chick embryos via oxidative stress and DNA methylation associated transcriptional down-regulation of miR-124

Although moderate homocysteine (HCY) elevation is associated with neural tube defects (NTDs), the underlying mechanisms have not been elucidated. In this study, we aimed to investigate that whether HCY-induced NTDs were associated with oxidative stress and methyl metabolism in chick embryos. The pot...

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Bibliographic Details
Published in:Toxicol Res (Camb)
Main Authors: Wang, Rui, Han, Zhong-Ji, Song, Ge, Cui, Yi, Xia, Hong-Fei, Ma, Xu
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201575/
https://ncbi.nlm.nih.gov/pubmed/34141156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxres/tfab020
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