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Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine-resistant myeloid leukemia cells

Cytarabine is a key chemotherapy drug for treating leukemia; however, chemotherapy-induced multidrug resistance is a major cause of therapy failure or tumor recurrence. Current medical treatment strategies still cannot address the issue of multidrug resistance phenotypes in the treatment of leukemia...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Med Rep
Auteurs principaux: Tseng, Yu-Hsin, Yang, Rei-Cheng, Chiou, Shyh-Shin, Shieh, Tzong-Ming, Shih, Yin-Hwa, Lin, Pei-Chin
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201441/
https://ncbi.nlm.nih.gov/pubmed/34109436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12204
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