Inhibition of Carbonic Anhydrase IX Promotes Apoptosis through Intracellular pH Level Alterations in Cervical Cancer Cells

Carbonic anhydrase IX (CAIX) is a hypoxia-related protein that plays a role in proliferation in solid tumours. However, how CAIX increases proliferation and metastasis in solid tumours is unclear. The objective of this study was to investigate how a synthetic CAIX inhibitor triggers apoptosis in the...

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發表在:Int J Mol Sci
Main Authors: Temiz, Ebru, Koyuncu, Ismail, Durgun, Mustafa, Caglayan, Murat, Gonel, Ataman, Güler, Eray Metin, Kocyigit, Abdurrahim, Supuran, Claudiu T.
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201173/
https://ncbi.nlm.nih.gov/pubmed/34198834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116098
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