Selective inhibition of carbonic anhydrase-IX by sulphonamide derivatives induces pH and reactive oxygen species-mediated apoptosis in cervical cancer HeLa cells

Selective inhibition with sulphonamides of carbonic anhydrase (CA) IX reduces cell proliferation and induces apoptosis in human cancer cells. The effect on CA IX expression of seven previously synthesised sulphonamide inhibitors, with high affinity for CA IX, as well as their effect on the prolifera...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Enzyme Inhib Med Chem
Egile Nagusiak: Koyuncu, Ismail, Gonel, Ataman, Kocyigit, Abdurrahim, Temiz, Ebru, Durgun, Mustafa, Supuran, Claudiu T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2018
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052416/
https://ncbi.nlm.nih.gov/pubmed/30001631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1481403
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