Yes-Associated Protein (Yap) Is Up-Regulated in Heart Failure and Promotes Cardiac Fibroblast Proliferation

Left ventricular (LV) heart failure (HF) is a significant and increasing cause of death worldwide. HF is characterized by myocardial remodeling and excessive fibrosis. Transcriptional co-activator Yes-associated protein (Yap), the downstream effector of HIPPO signaling pathway, is an essential facto...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Sharifi-Sanjani, Maryam, Berman, Mariah, Goncharov, Dmitry, Alhamaydeh, Mohammad, Avolio, Theodore Guy, Baust, Jeffrey, Chang, Baojun, Kobir, Ahasanul, Ross, Mark, St. Croix, Claudette, Nouraie, Seyed Mehdi, McTiernan, Charles F., Moravec, Christine S., Goncharova, Elena, Al Ghouleh, Imad
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201133/
https://ncbi.nlm.nih.gov/pubmed/34200497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116164
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