SPECT/CT Imaging, Biodistribution and Radiation Dosimetry of a (177)Lu-DOTA-Integrin αvβ6 Cystine Knot Peptide in a Pancreatic Cancer Xenograft Model

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant neoplasms, as many cases go undetected until they reach an advanced stage. Integrin αvβ6 is a cell surface receptor overexpressed in PDAC. Consequently, it may serve as a target for the development of probe...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Sachindra, Sachindra, Hellberg, Teresa, Exner, Samantha, Prasad, Sonal, Beindorff, Nicola, Rogalla, Stephan, Kimura, Richard, Gambhir, Sanjiv Sam, Wiedenmann, Bertram, Grötzinger, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200818/
https://ncbi.nlm.nih.gov/pubmed/34136410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.684713
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