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Influence of DOTA Chelators on Radiochemical Purity and Biodistribution of (177)Lu- and (90)Y-Rituximab in Xenografted Mice

This work presents a comparative biological evaluation of (90)Y- and (177)Lu- labelled DOTA-SCN and DOTA-NHS conjugated to Rituximab in tumour-bearing mice. Two DOTA derivatives, p-SCN-Bn-DOTA and DOTA-NHS-ester were conjugated to Rituximab and then freeze-dried kit formulations were prepared, as pr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Iran J Pharm Res
मुख्य लेखकों: Karczmarczyk, Urszula, Wojdowska, Wioletta, Mikołajczak, Renata, Maurin, Michał, Laszuk, Ewa, Garnuszek, Piotr
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Shaheed Beheshti University of Medical Sciences 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269569/
https://ncbi.nlm.nih.gov/pubmed/30568680
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