Aerobic Exercise Restores Aging‐Associated Reductions in Arterial Adropin Levels and Improves Adropin‐Induced Nitric Oxide‐Dependent Vasorelaxation

BACKGROUND: Adropin is a peptide hormone that promotes nitric oxide (NO) production via activation of endothelial NO synthase (eNOS) in endothelial cells. Its circulating levels are reduced with aging and increased with aerobic exercise training (AT). Using a mouse model, we hypothesized that AT res...

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Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Autores principales: Fujie, Shumpei, Hasegawa, Natsuki, Horii, Naoki, Uchida, Masataka, Sanada, Kiyoshi, Hamaoka, Takafumi, Padilla, Jaume, Martinez‐Lemus, Luis A., Maeda, Seiji, Iemitsu, Motoyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200711/
https://ncbi.nlm.nih.gov/pubmed/33938228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.020641
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