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Aerobic Exercise Restores Aging‐Associated Reductions in Arterial Adropin Levels and Improves Adropin‐Induced Nitric Oxide‐Dependent Vasorelaxation

BACKGROUND: Adropin is a peptide hormone that promotes nitric oxide (NO) production via activation of endothelial NO synthase (eNOS) in endothelial cells. Its circulating levels are reduced with aging and increased with aerobic exercise training (AT). Using a mouse model, we hypothesized that AT res...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Fujie, Shumpei, Hasegawa, Natsuki, Horii, Naoki, Uchida, Masataka, Sanada, Kiyoshi, Hamaoka, Takafumi, Padilla, Jaume, Martinez‐Lemus, Luis A., Maeda, Seiji, Iemitsu, Motoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200711/
https://ncbi.nlm.nih.gov/pubmed/33938228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.020641
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