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Connectivity Map Analysis Indicates PI3K/Akt/mTOR Inhibitors as Potential Anti-Hypoxia Drugs in Neuroblastoma

SIMPLE SUMMARY: A large percentage of patients with neuroblastoma relapse and die, despite treatment, thus demanding new personalized strategies and therapeutic targets. Hypoxia, a condition of reduced oxygenation in several solid tumors, has profound effects on the neuroblastoma (NB) tumor biology...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Uva, Paolo, Bosco, Maria Carla, Eva, Alessandra, Conte, Massimo, Garaventa, Alberto, Amoroso, Loredana, Cangelosi, Davide
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200206/
https://ncbi.nlm.nih.gov/pubmed/34199959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112809
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