Patterns and Prevalence of BRCA1 and BRCA2 Germline Mutations Among Patients with Triple-Negative Breast Cancer: Regional Perspectives

BACKGROUND: Among all subtypes, patients with triple-negative (TN) breast cancer is known for their poor outcome and their higher risk of harboring BRCA1 or BRCA2 pathogenic mutations. Identification of such mutations has clinical impact on breast and ovarian cancer prevention and treatment decision...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Abdel-Razeq, Hikmat, Tamimi, Faris, Abujamous, Lama, Edaily, Sara, Abunasser, Mahmoud, Bater, Rayan, Salama, Osama
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200144/
https://ncbi.nlm.nih.gov/pubmed/34135636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S316470
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