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Patterns and Prevalence of Germline BRCA1 and BRCA2 Mutations among High-Risk Breast Cancer Patients in Jordan: A Study of 500 Patients

PURPOSE: Knowledge of BRCA1 and BRCA2 mutations has a significant clinical impact on the management and prevention of breast cancer. In this study, we evaluate the pattern and prevalence of germline mutations in BRCA1 and BRCA2 among high-risk Jordanian breast cancer patients selected as per interna...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Oncol
Hauptverfasser: Abdel-Razeq, Hikmat, Abujamous, Lama, Jadaan, Dima
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376431/
https://ncbi.nlm.nih.gov/pubmed/32733560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8362179
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