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Off-Target-Based Design of Selective HIV-1 PROTEASE Inhibitors

The approval of the first HIV-1 protease inhibitors (HIV-1 PRIs) marked a fundamental step in the control of AIDS, and this class of agents still represents the mainstay therapy for this illness. Despite the undisputed benefits, the necessary lifelong treatment led to numerous severe side-effects (m...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Monica, Gabriele La, Lauria, Antonino, Bono, Alessia, Martorana, Annamaria
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200130/
https://ncbi.nlm.nih.gov/pubmed/34199858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116070
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