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Use of high-content imaging to quantify transduction of AAV-PHP viruses in the brain following systemic delivery
The engineering of the AAV-PHP capsids was an important development for CNS research and the modulation of gene expression in the brain. They cross the blood brain barrier and transduce brain cells after intravenous systemic delivery, a property dependent on the genotype of Ly6a, the AAV-PHP capsid...
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| Veröffentlicht in: | Brain Commun |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8200048/ https://ncbi.nlm.nih.gov/pubmed/34131644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcab105 |
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