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DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat
As we age, our bodies accrue damage in the form of DNA mutations. These mutations lead to the generation of sub-optimal proteins, resulting in inadequate cellular homeostasis and senescence. The build-up of senescent cells negatively affects the local cellular micro-environment and drives ageing ass...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8199619/ https://ncbi.nlm.nih.gov/pubmed/34199458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116011 |
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