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DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat

As we age, our bodies accrue damage in the form of DNA mutations. These mutations lead to the generation of sub-optimal proteins, resulting in inadequate cellular homeostasis and senescence. The build-up of senescent cells negatively affects the local cellular micro-environment and drives ageing ass...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Boughey, Harvey, Jurga, Mateusz, El-Khamisy, Sherif F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199619/
https://ncbi.nlm.nih.gov/pubmed/34199458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116011
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