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β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells

The naked mole-rat (NMR; Heterocephalus glaber) exhibits cancer resistance and an exceptionally long lifespan of approximately 30 years, but the mechanism(s) underlying increased longevity in NMRs remains unclear. In the present study, we report unique mechanisms underlying cholesterol metabolism in...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Chee, Woei-Yaw, Kurahashi, Yuriko, Kim, Junhyeong, Miura, Kyoko, Okuzaki, Daisuke, Ishitani, Tohru, Kajiwara, Kentaro, Nada, Shigeyuki, Okano, Hideyuki, Okada, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979689/
https://ncbi.nlm.nih.gov/pubmed/33742113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01879-8
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