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Novel Bis- and Mono-Pyrrolo[2,3-d]pyrimidine and Purine Derivatives: Synthesis, Computational Analysis and Antiproliferative Evaluation

Novel symmetrical bis-pyrrolo[2,3-d]pyrimidines and bis-purines and their monomers were synthesized and evaluated for their antiproliferative activity in human lung adenocarcinoma (A549), cervical carcinoma (HeLa), ductal pancreatic adenocarcinoma (CFPAC-1) and metastatic colorectal adenocarcinoma (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Bistrović Popov, Andrea, Vianelo, Robert, Grbčić, Petra, Sedić, Mirela, Pavelić, Sandra Kraljević, Pavelić, Krešimir, Raić-Malić, Silvana
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199500/
https://ncbi.nlm.nih.gov/pubmed/34206076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26113334
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