Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa

The ability of spermatozoa to swim towards an oocyte and fertilize it depends on precise K(+) permeability changes. Kir5.1 is an inwardly-rectifying potassium (Kir) channel with high sensitivity to intracellular H(+) (pHi) and extracellular K(+) concentration [K(+)](o), and hence provides a link bet...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Poli, Giulia, Hasan, Sonia, Belia, Silvia, Cenciarini, Marta, Tucker, Stephen J., Imbrici, Paola, Shehab, Safa, Pessia, Mauro, Brancorsini, Stefano, D’Adamo, Maria Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199489/
https://ncbi.nlm.nih.gov/pubmed/34205849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115972
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