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Impact of SGLT2 Inhibitors on Heart Failure: From Pathophysiology to Clinical Effects

Heart failure (HF) affects up to over 20% of patients with type 2 diabetes (T2DM), even more in the elderly. Although, in T2DM, both hyperglycemia and the proinflammatory status induced by insulin resistance are crucial in cardiac function impairment, SGLT2i cardioprotective mechanisms against HF ar...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Palmiero, Giuseppe, Cesaro, Arturo, Vetrano, Erica, Pafundi, Pia Clara, Galiero, Raffaele, Caturano, Alfredo, Moscarella, Elisabetta, Gragnano, Felice, Salvatore, Teresa, Rinaldi, Luca, Calabrò, Paolo, Sasso, Ferdinando Carlo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199383/
https://ncbi.nlm.nih.gov/pubmed/34070765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115863
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