Impact of SGLT2 Inhibitors on Heart Failure: From Pathophysiology to Clinical Effects

Heart failure (HF) affects up to over 20% of patients with type 2 diabetes (T2DM), even more in the elderly. Although, in T2DM, both hyperglycemia and the proinflammatory status induced by insulin resistance are crucial in cardiac function impairment, SGLT2i cardioprotective mechanisms against HF ar...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Palmiero, Giuseppe, Cesaro, Arturo, Vetrano, Erica, Pafundi, Pia Clara, Galiero, Raffaele, Caturano, Alfredo, Moscarella, Elisabetta, Gragnano, Felice, Salvatore, Teresa, Rinaldi, Luca, Calabrò, Paolo, Sasso, Ferdinando Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199383/
https://ncbi.nlm.nih.gov/pubmed/34070765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115863
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