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5-HT(1A) Serotonergic, α-Adrenergic and Opioidergic Receptors Mediate the Analgesic Efficacy of Vortioxetine in Mice

Vortioxetine is a multimodal antidepressant drug that affects several brain neurochemicals and has the potential to induce various pharmacological effects on the central nervous system. Therefore, we investigated the centrally mediated analgesic efficacy of this drug and the mechanisms underlying th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Turan Yücel, Nazlı, Kandemir, Ümmühan, Demir Özkay, Ümide, Can, Özgür Devrim
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199248/
https://ncbi.nlm.nih.gov/pubmed/34071269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26113242
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