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Pharmacophore-Based Virtual Screening of Novel Competitive Inhibitors of the Neurodegenerative Disease Target Kynurenine-3-Monooxygenase

The pathogenesis of several neurodegenerative diseases such as Alzheimer’s or Huntington’s disease has been associated with metabolic dysfunctions caused by imbalances in the brain and cerebral spinal fluid levels of neuroactive metabolites. Kynurenine monooxygenase (KMO) is considered an ideal ther...

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Publicat a:Molecules
Autors principals: Gotina, Lizaveta, Seo, Seon Hee, Kim, Chae Won, Lim, Sang Min, Pae, Ae Nim
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199213/
https://ncbi.nlm.nih.gov/pubmed/34073016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26113314
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