TNFα Enhances Tamoxifen Sensitivity through Dissociation of ERα-p53-NCOR1 Complexes in ERα-Positive Breast Cancer

SIMPLE SUMMARY: Tamoxifen has been clinically applied as a central chemotherapeutic agent for treatment of estrogen receptor (ER)-positive breast cancer. However, many ER-positive breast cancer patients with the high ER level demonstrate intrinsic resistance against the tamoxifen therapy. The aim of...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Kim, Hyunhee, Park, Seung-Ho, Lee, Jangho, Sung, Gi-Jun, Song, Ji-Hye, Kwak, Sungmin, Jeong, Ji-Hoon, Kong, Min-Jeong, Hwang, Jin-Taek, Choi, Hyo-Kyoung, Choi, Kyung-Chul
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199199/
https://ncbi.nlm.nih.gov/pubmed/34073371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112601
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