Combined Gemcitabine and Immune-Checkpoint Inhibition Conquers Anti-PD-L1 Resistance in Low-Immunogenic Mismatch Repair-Deficient Tumors

Tumors arising in the context of Lynch Syndrome or constitutional mismatch repair deficiency are hypermutated and have a good response towards immune-checkpoint inhibitors (ICIs), including α-PD-L1 antibodies. However, in most cases, resistance mechanisms evolve. To improve outcomes and prevent resi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Salewski, Inken, Henne, Julia, Engster, Leonie, Schneider, Bjoern, Lemcke, Heiko, Skorska, Anna, Berlin, Peggy, Henze, Larissa, Junghanss, Christian, Maletzki, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199186/
https://ncbi.nlm.nih.gov/pubmed/34206051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115990
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados