Overcoming PD-1 Inhibitor Resistance with a Monoclonal Antibody to Secreted Frizzled-Related Protein 2 in Metastatic Osteosarcoma

SIMPLE SUMMARY: Osteosarcoma (OS) is the most common bone tumor in the pediatric population, and long-term survival occurs in less than a third of the population with metastatic or recurrent tumors. Secreted frizzled-related protein 2 (SFRP2) promotes metastatic OS cell migration and tumor angiogene...

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Publicado en:Cancers (Basel)
Autores principales: Nasarre, Patrick, Garcia, Denise I., Siegel, Julie B., Bonilla, Ingrid V., Mukherjee, Rupak, Hilliard, Eleanor, Chakraborty, Paramita, Nasarre, Cécile, Yustein, Jason T., Lang, Margaret, Jaffa, Aneese A., Mehrotra, Shikhar, Klauber-DeMore, Nancy
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199140/
https://ncbi.nlm.nih.gov/pubmed/34070758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112696
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