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Frizzled-5: A High Affinity Receptor for Secreted Frizzled-Related Protein-2 Activation of Nuclear Factor of Activated T-Cells c3 Signaling to Promote Angiogenesis
Secreted frizzled-related protein 2 (SFRP2) is a pro-angiogenic factor expressed in the vasculature of a wide variety of human tumors, and modulates angiogenesis via the calcineurin-dependent Nuclear Factor of Activated T-cells cytoplasmic 3 (NFATc3) pathway in endothelial cells. However, until now,...
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| Published in: | Angiogenesis |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5675522/ https://ncbi.nlm.nih.gov/pubmed/28840375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-017-9574-5 |
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