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Frizzled-5: A High Affinity Receptor for Secreted Frizzled-Related Protein-2 Activation of Nuclear Factor of Activated T-Cells c3 Signaling to Promote Angiogenesis

Secreted frizzled-related protein 2 (SFRP2) is a pro-angiogenic factor expressed in the vasculature of a wide variety of human tumors, and modulates angiogenesis via the calcineurin-dependent Nuclear Factor of Activated T-cells cytoplasmic 3 (NFATc3) pathway in endothelial cells. However, until now,...

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Bibliographic Details
Published in:Angiogenesis
Main Authors: Peterson, Yuri K., Nasarre, Patrick, Bonilla, Ingrid V., Hilliard, Eleanor, Samples, Jennifer, Morinelli, Thomas A., Hill, Elizabeth G., Klauber-DeMore, Nancy
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675522/
https://ncbi.nlm.nih.gov/pubmed/28840375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-017-9574-5
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