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FLT3 Tyrosine Kinase Inhibitors for the Treatment of Fit and Unfit Patients with FLT3-Mutated AML: A Systematic Review

FLT3-mutated acute myeloid leukemia accounts for around 30% of acute myeloid leukemia (AML). The mutation carried a poor prognosis until the rise of tyrosine kinase inhibitors (TKIs). New potent and specific inhibitors have successfully altered the course of the disease, increasing the complete resp...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Loschi, Michael, Sammut, Rinzine, Chiche, Edmond, Cluzeau, Thomas
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198781/
https://ncbi.nlm.nih.gov/pubmed/34070902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115873
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