A role for protease activated receptor type 3 (PAR3) in nociception demonstrated through development of a novel peptide agonist

The protease activated receptor (PAR) family is a group of G-protein coupled receptors (GPCRs) activated by proteolytic cleavage of the extracellular domain. PARs are expressed in a variety of cell types with crucial roles in hemostasis, immune responses, inflammation, and pain. PAR3 is the least re...

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Détails bibliographiques
Publié dans:J Pain
Auteurs principaux: Mwirigi, Juliet, Kume, Moeno, Hassler, Shayne N, Ahmad, Ayesha, Ray, Pradipta R, Jiang, Changyu, Chamessian, Alexander, Mseeh, Nakleh, Ludwig, Breya P, Rivera, Benjamin D., Nieman, Marvin T, Van de Ven, Thomas, Ji, Ru-Rong, Dussor, Gregory, Boitano, Scott, Vagner, Josef, Price, Theodore J
Format: Artigo
Langue:Inglês
Publié: 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197731/
https://ncbi.nlm.nih.gov/pubmed/33429107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2020.12.006
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