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O-GlcNAcylation Prediction: An Unattained Objective

BACKGROUND: O-GlcNAcylation is an essential post-translational modification (PTM) in mammalian cells. It consists in the addition of a N-acetylglucosamine (GlcNAc) residue onto serines or threonines by an O-GlcNAc transferase (OGT). Inhibition of OGT is lethal, and misregulation of this PTM can lead...

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Pubblicato in:Adv Appl Bioinform Chem
Autori principali: Mauri, Theo, Menu-Bouaouiche, Laurence, Bardor, Muriel, Lefebvre, Tony, Lensink, Marc F, Brysbaert, Guillaume
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197665/
https://ncbi.nlm.nih.gov/pubmed/34135600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/AABC.S294867
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