The Combination Immunotherapy of TLR9 Agonist and OX40 Agonist via Intratumoural Injection for Hepatocellular Carcinoma

BACKGROUND: The response rate of immunotherapy via immune checkpoint blockade in hepatocellular carcinoma (HCC) is limited due to multiple immune evasion mechanisms. OX40 is a T cell co-stimulating molecule which suppresses the cancer immune evasion by activating effector T cells (Teffs) and counter...

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Detalhes bibliográficos
Publicado no:J Hepatocell Carcinoma
Main Authors: Zhou, Zhimei, Lin, Liteng, An, Yongcheng, Zhan, Meixiao, Chen, Ye, Cai, Mingyue, Zhu, Xiaojing, Lu, Ligong, Zhu, Kangshun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197594/
https://ncbi.nlm.nih.gov/pubmed/34136421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JHC.S301375
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