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Folate Receptor Beta as a Direct and Indirect Target for Antibody-Based Cancer Immunotherapy

Folate receptor beta (FRβ) is a folate binding receptor expressed on myeloid lineage hematopoietic cells. FRβ is commonly expressed at high levels on malignant blasts in patients with acute myeloid leukemia (AML), as well as on M2 polarized tumor-associated macrophages (TAMs) in the tumor microenvir...

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Publicat a:Int J Mol Sci
Autors principals: Roy, Allison G., Robinson, J. Michael, Sharma, Prannda, Rodriguez-Garcia, Alba, Poussin, Mathilde A., Nickerson-Nutter, Cheryl, Powell, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197521/
https://ncbi.nlm.nih.gov/pubmed/34070369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115572
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