Učitavanje...
An apparent core/shell architecture of polyQ aggregates in the aging Caenorhabditis elegans neuron
Huntington's disease is caused by a polyglutamine (polyQ) expansion in the huntingtin protein which results in its abnormal aggregation in the nervous system. Huntingtin aggregates are linked to toxicity and neuronal dysfunction, but a comprehensive understanding of the aggregation mechanism in...
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| Izdano u: | Protein Sci |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley & Sons, Inc.
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8197433/ https://ncbi.nlm.nih.gov/pubmed/33966305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4105 |
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