Tafazzin Deficiency Reduces Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets From Male Mice

Tafazzin (TAZ) is a cardiolipin (CL) biosynthetic enzyme important for maintaining mitochondrial function. TAZ affects both the species and content of CL in the inner mitochondrial membrane, which are essential for normal cellular respiration. In pancreatic β cells, mitochondrial function is closely...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Cole, Laura K, Agarwal, Prasoon, Doucette, Christine A, Fonseca, Mario, Xiang, Bo, Sparagna, Genevieve C, Seshadri, Nivedita, Vandel, Marilyne, Dolinsky, Vernon W, Hatch, Grant M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197286/
https://ncbi.nlm.nih.gov/pubmed/34019639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqab102
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