Tafazzin Deficiency Reduces Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets From Male Mice

Tafazzin (TAZ) is a cardiolipin (CL) biosynthetic enzyme important for maintaining mitochondrial function. TAZ affects both the species and content of CL in the inner mitochondrial membrane, which are essential for normal cellular respiration. In pancreatic β cells, mitochondrial function is closely...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Cole, Laura K, Agarwal, Prasoon, Doucette, Christine A, Fonseca, Mario, Xiang, Bo, Sparagna, Genevieve C, Seshadri, Nivedita, Vandel, Marilyne, Dolinsky, Vernon W, Hatch, Grant M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197286/
https://ncbi.nlm.nih.gov/pubmed/34019639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqab102
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