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Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy
ADAM17 is a disintegrin and metalloproteinase capable of cleaving the ectodomains of a diverse variety of molecules including TNF-α, TGF-α, L-selectin, and ACE2. We have previously demonstrated that renal ADAM17 is upregulated in diabetic mice. The role of endothelial (eAdam17) and proximal tubular...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8197223/ https://ncbi.nlm.nih.gov/pubmed/34073747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115520 |
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