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Inhibition of DNA Repair in Combination with Temozolomide or Dianhydrogalactiol Overcomes Temozolomide-Resistant Glioma Cells

SIMPLE SUMMARY: Glioblastoma is the most prevalent and lethal brain tumor. Temozolomide is usually used for the treatment of glioblastoma. The poor prognosis of the tumor is due to drug resistance and tumor heterogeneity. The mechanism of the resistance to temozolomide is various within the same tum...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Ohba, Shigeo, Yamashiro, Kei, Hirose, Yuichi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197190/
https://ncbi.nlm.nih.gov/pubmed/34073837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112570
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