Insight into Bortezomib Focusing on Its Efficacy against P-gp-Positive MDR Leukemia Cells

In this paper, we compared the effects of bortezomib on L1210 (S) cells with its effects on P-glycoprotein (P-gp)-positive variant S cells, which expressed P-gp either after selection with vincristine (R cells) or after transfection with a human gene encoding P-gp (T cells). Bortezomib induced the d...

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Publicado en:Int J Mol Sci
Autores principales: Kyca, Tomáš, Pavlíková, Lucia, Boháčová, Viera, Mišák, Anton, Poturnayová, Alexandra, Breier, Albert, Sulová, Zdena, Šereš, Mário
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197160/
https://ncbi.nlm.nih.gov/pubmed/34071136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115504
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