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Overexpression of GRP78/BiP in P-Glycoprotein-Positive L1210 Cells is Responsible for Altered Response of Cells to Tunicamycin as a Stressor of the Endoplasmic Reticulum

P-glycoprotein (P-gp, ABCB1 member of the ABC (ATP-binding cassette) transporter family) localized in leukemia cell plasma membranes is known to reduce cell sensitivity to a large but well-defined group of chemicals known as P-gp substrates. However, we found previously that P-gp-positive sublines o...

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Vydáno v:Cells
Hlavní autoři: Šereš, Mário, Pavlíková, Lucia, Boháčová, Viera, Kyca, Tomáš, Borovská, Ivana, Lakatoš, Boris, Breier, Albert, Sulová, Zdena
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226765/
https://ncbi.nlm.nih.gov/pubmed/32268491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040890
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